Misaki Suzuhara is a 12-year-old Middle School Freshman (7th grader) who just moved to Tokyo. She sees a show that features two doll-like toys fighting, and she is interested in it. Icchan, a strange man in a laboratory coat and glasses, takes her to a toy store and introduces her to those dolls and the fighting going on with it: Angelic Layer. Misaki meets friends interested in Angelic Layer and enters Angelic Layer tournaments, becoming a major competitor, even as a newbie.